发明名称 |
LIQUID INJECTABLE FORMULATION OF DISODIUM PAMIDRONATE |
摘要 |
The present invention relates to an improved injectable ready to use preparation of pamidronate salts, methods for its manufacture and uses of the solution of the invention in the manufacture of pharmaceutical compositions for the treatment of diseases selected from the group of tumour-induced hypercalcaemia, Paget's disease, osteoporosis, bone metastases, or breast cancer. The ready to use solution comprises a physiologically acceptable alkaline salt which is water soluble and a physiologically acceptable aqueous solvent having a concentration of between 0.1 and 100 mg/mL which has not been reconstituted from a lyophilizate, wherein the solution is provided in a sealed non-reactive container.
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申请公布号 |
WO02089768(A1) |
申请公布日期 |
2002.11.14 |
申请号 |
WO2001CA01617 |
申请日期 |
2001.11.15 |
申请人 |
PHARMACEUTICAL PARTNERS OF CANADA INC.;HAHN, SAM;SZYMANSKI, DENNIS |
发明人 |
HAHN, SAM;SZYMANSKI, DENNIS |
分类号 |
A61K9/00;A61K9/08;A61K31/663;A61K47/02;A61K47/26;A61P19/08;A61P19/10;A61P35/04;(IPC1-7):A61K9/08 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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