发明名称 |
NOVEL MACROPHAGE FOAM CELL FORMATION INHIBITOR FKA-25 AND P ROCESS FOR PRODUCING THE SAME |
摘要 |
<p>The present invention relates to a novel FKA-25 substance, which inhibits formation of the foam macrophage originated from mouse, having inhibitory action against formation of the foam macrophage and a process for production thereof. The process includes culturing Pseudobotrytis sp. FKA-25 belonging to genus Pseudobotrytis sp. and having ability to produce FKA-25 substance in a medium, accumulating FKA-25 substance in the cultured medium, and collecting FKA-25 substance from the cultured mass. The obtained FKA-25 substance specifically inhibits the formation of the foam macrophage originated from mouse and is expected to be useful for prevention and treatment of arteriosclerosis and causative diseases therefrom.</p> |
申请公布号 |
EP1550727(A1) |
申请公布日期 |
2005.07.06 |
申请号 |
EP20020777831 |
申请日期 |
2002.10.11 |
申请人 |
THE KITASATO INSTITUTE |
发明人 |
OMURA, SATOSHI;TOMODA, HIROSHI;MASUMA, ROKURO |
分类号 |
A61P3/06;A61P9/00;A61P9/10;A61P43/00;C07D405/06;C12P17/16;(IPC1-7):C12P17/10;A61K31/403 |
主分类号 |
A61P3/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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