METHOD AND DEVICE FOR THE DETECTION AND QUANTIFICATION OF A CHEMICAL COMPOUND IN A FLUID STREAM

摘要

The invention relates to a method which can be used to collect a chemical compound, typically an impurity, and accumulate said chemical compound on a scavenger mass CAPT in at least one removable adsorbent cartridge MC for a period of more than two days, for the purpose of external chemical analysis. The invention also relates to a suitable device ST for collecting at least one chemical compound from a fluid stream for the detection and/or quantification thereof, including, downstream of the aforementioned cartridge(s), at least one means for measuring the cumulative flow having passed through said cartridge(s) during a pre-determined period of time. In a preferred embodiment of the invention, the scavenger mass CAPT is divided into a plurality of elementary masses CAPTi, thereby enabling the evaluation of the spread of an irreversible adsorption front or the movement of a chromatographic zone.