发明名称 |
Anti human interleukin-1 receptor accessory protein (IL1 RAP) antibodies and uses thereof |
摘要 |
The present disclosure provides an antibody or an antigen-binding fragment thereof with binding specificity for human interleukin-1 receptor accessory protein (IL1 RAP) wherein the antibody or antigen-binding fragment is capable of inhibiting the binding of antibody 'CAN04' to human IL1 RAP. The disclosure further provides the use of such antibodies or an antigen-binding fragments in the treatment and/or diagnosis of IL-1 associated diseases and conditions, including cancers such as acute myeloid leukemia and melanoma. |
申请公布号 |
AU2015225948(A1) |
申请公布日期 |
2016.09.08 |
申请号 |
AU20150225948 |
申请日期 |
2015.03.05 |
申请人 |
CANTARGIA AB |
发明人 |
AGERSTAM, HELENA;FIORETOS, THOAS;JARAS, MARCUS;MALMBORG HAGER, CECILIA ANN-CHRISTIN;SJOSTROM, KJELL;SVEDBERG, AGNETA;VON WACHENFELDT, KARIN |
分类号 |
C07K16/28;A61K39/395;A61P35/00 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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