AROMATISCHE HYDROXY- ODER THIOL-DERIVATE VON CARBONSAEUREESTERN ALS LIPASESUBSTRATE.

摘要

Lipase substrates of formula (I) are new. A=1-16C alkylene or alkenylene; R, R1=1-20C alkyl, alkenyl or acyl or aryl or aralkyl opt. substd. by 1-8C alkyl, and one of R and R1 can also be H; X=residue of an aromatic hydroxy or thiol cpd. Procedure for the optical determination of lipase is new when a substrate of formula (I) is subjected to the action of a lipase-contg. specimen and the amt. of aromatic hydroxy or thiol cpd. released or the amt. of dye formed after coupling with a suitable chromogen is determined optically. Reagents for the optical determn. of lipase are new when they contain one or more cpds. of formula (I) and a buffer substance, as well as bile acid alkali salt, calipase, salt, urea and/or a chromogenic coupler.