| 摘要 |
<p>The invention relates to a medical device useful for the localized delivery of a therapeutic agent having at least one blood-contacting surface comprising a porous material having dispersed therein an elutable therapeutic agent. Preferred devices include a structure including a porous polymeric material and an elutable therapeutic agent in the form of a solid, gel, or neat liquid, which is dispersed in at least a portion of the porous polymeric material. Methods for making a medical device having a blood-contacting surface are also provided. One method includes the use of a concentrating agent whereby to localise the therapeutic agent within the porous material. Another method involves multiple immersion steps without the use of a concentrating agent.</p> |
