COMBINATORIAL THERAPY OF CANCER AND INFECTIOUS DISEASES WITHANTI-B7-H1 ANTIBODIES
摘要
<p>Described are uses of an agent that reduces B7-H1 interaction with PD-I, and particularly monoclonal antibodies that bind to B7-H1 and interfere with B7-H1 interaction with PD-I in combination with a vaccine to provide synerg istic effects. The application provides methods of treatment and vaccination based on the combination of these compounds on T cell responses.</p>
申请公布号
CA2663521(A1)
申请公布日期
2008.07.17
申请号
CA20072663521
申请日期
2007.09.20
申请人
THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE
发明人
CHEN, LIEPING;PARDOLL, DREW;DRAKE, CHARLES;COX, ANDREA