Protein kinase inhibitors (variants), use thereof in treating oncological diseases and a pharmaceutical composition based thereon

摘要

The present invention relates to the treatment of oncological, chronic inflammatory and similar diseases with the aid of new families of chemical compounds having improved efficiency with regard to the inhibition of Abl kinase and mutant forms thereof, as well as other therapeutically significant kinases. It describes protein kinase inhibitors in the form of compounds of general formula (I) and compounds of general formula (II), or a tautomer, an individual isomer, a mixture of isomers, a pharmaceutically acceptable salt, a solvate or a hydrate thereof.;

主权项

1. A compound selected from compounds of the following structures, or a pharmaceutically acceptable salt thereof: