| 摘要 |
A compound of formula (I) or a salt thereof, or a solvate thereof, wherein: X represents oxygen, sulphur, or NR<SUB>b</SUB>; Y and Z each independently represent nitrogen, CH, CR<SUB>1 </SUB>or CR<SUB>2</SUB>; A represents an unsubstituted or substituted aryl group or an unsubstituted or substituted heterocyclyl group; R<SUB>a </SUB>represents -C(O)NR<SUB>s</SUB>R<SUB>t</SUB>; R<SUB>1 </SUB>and R<SUB>2 </SUB>each independently represents hydrogen or specific substituents; and the use of such a compound in the treatment and/or prophylaxis of diseases associated with over activity of osteoclasts in mammals.
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