| 发明名称 |
Triamine chelants, their derivatives, complexes and conjugates |
| 摘要 |
A group of functionalized triamine chelants and their derivatives that form complexes with radioactive metal ions are disclosed. The complexes can be covalently attached to a protein or an antibody or antibody fragment and used for therapeutic and/or diagnostic purposes. The chelants are of the formula: <IMAGE> wherein n, m, R, R1, R2 and L are defined in the specification.
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| 申请公布号 |
US5395608(A) |
申请公布日期 |
1995.03.07 |
| 申请号 |
US19910697861 |
申请日期 |
1991.05.09 |
| 申请人 |
THE CURATORS OF THE UNIVERSITY OF MISSOURI |
发明人 |
TROUTNER, DAVID E.;JOHN, CHRISTY S.;PILLAI, MAROOR R. A. |
| 分类号 |
A61K51/10;C07C215/50;C07C251/38;C07D207/32;C07D207/335;C07D213/38;C07F13/00;(IPC1-7):A61K49/00;A61K35/14;C07C211/00 |
主分类号 |
A61K51/10 |
| 代理机构 |
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代理人 |
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| 主权项 |
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