摘要 |
<p>Compounds of formula (I): <CHEM> Äin which: X represents an optionally substituted benzimidazole group; Y represents an oxygen or sulphur atom; Z represents a 2,4-dioxothiazolidin-5-ylidenylmethyl, 2,4-dioxothiazolidin-5-ylmethyl, 2,4-dioxo-oxazolidin-5-ylmethyl, 3,5-dioxooxadiazolidin-2-ylmethyl or N-hydroxyureidomethyl group; R represents hydrogen, alkyl, alkoxy, halogen, hydroxy, nitro, amino or aralkyl; and m is an integer from 1 to 5Ü; have valuable activity for the treatment and/or prophylaxis of a variety of disorders, including one or more of: hyperlipemia, hyperglycemia, obesity, impaired glucose tolerance (IGT), insulin resistance and diabetic complications.</p> |
申请人 |
SANKYO COMPANY LIMITED |
发明人 |
FUJITA, TAKASHI;WADA, KUNIO;OGUCHI, MINORU;YANAGISAWA, HIROAKI;FUJIMOTO, KOICHI;FUJIWARA, TOSHIHIKO;HORIKOSHI, HIROYOSHI;YOSHIOKA, TAKAO |