发明名称 |
Method For Production of Optically Active Biphenylalanine Compound or Salt or Ester Thereof |
摘要 |
Disclosed is a method for production of an optically active biphenylalanine compound represented by the formula (2): (wherein, R2 is a protective group of an amino group, and R3 and R4 are each independently a hydrogen atom, etc.) or a salt thereof and an optically active biphenylalanine ester compound represented by the formula (3): (wherein, R1 is an alkyl group, etc.) wherein the method comprises hydrolyzing a biphenylalanine ester compound represented by the formula (1): with a protease produced by a microorganism belonging to Bacillus sp. in the presence of at least one alkali selected from an alkali metal hydroxide and an alkaline earth metal hydroxide.
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申请公布号 |
US2009011475(A1) |
申请公布日期 |
2009.01.08 |
申请号 |
US20070087753 |
申请日期 |
2007.01.15 |
申请人 |
SUGI KIYOSHI;TANAKA MASAHIDE;KAWADA YOSHIHIRO;SASAYAMA DAISUKE |
发明人 |
SUGI KIYOSHI;TANAKA MASAHIDE;KAWADA YOSHIHIRO;SASAYAMA DAISUKE |
分类号 |
C12P13/04;C07C227/40;C12P7/62 |
主分类号 |
C12P13/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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