| 主权项 |
1. A method for inhibiting a kinase activity of a kinase enzyme, the method comprising the step of providing a kinase inhibiting composition,
wherein the amino acid sequence of the kinase inhibiting peptide is WLRRIKAWLRRIKALARQLGVAA [SEQ ID NO: 113], and wherein the kinase enzyme contacts the kinase inhibiting composition, wherein the activity of the kinase enzyme is inhibited, and wherein the kinase enzyme is selected from the group consisting of: Ab 1, Akt/PKB, AMPK, Arg, Ask, Aurora-A, Axl, Blk, Bmx, Brk, BTK, CaMKI, CaMKIδ, CaMKIIβ, CaMKIγ, CaMKI1β, Casein Kinase, Cdk, CDK9/cyclin, CKly1, CKly2, CKly3, Ck1δ, CK2α, CK2, CHK, CDK1/cyclinB, CHK1, CHK2 mutants, CK1δ, CK2, c-Kit, CLK2, CLK3, Cott, Csk, DAPK1, DCAMKL2, DDR, DYRK2, EGFR, Ephs, EphA2, FAK, Fer, Fes/Fps, FGFR, FGFR1, Fgr, Fit, Flt3, Flt4, Fms/CSF-1 R, Fyn, GRK5, GRK6, GRK7, GSK, GSK3, Hck, HER/ErbB, HIPK1, HIPK2, HIPK3, IGF-1R, ICF IR, IKK, Insulin R, IRAK, IRAK1, IRAK4, JAK, JAK1, JAK2, JAK3, JNK/SAPK, KDR, Lck, LIMK, LIMK1, LOK, Lyn, MAPK, MAPK1, MAPKAP Kinase, MEK, MEK1, MELK, Met, Mer, MINK, MKK, MLCK, MLK1, MRCKa, MSK1, MST, MST3, NEK, NEK3, NEK9, PDGFR, PDGFRα, PDGFRβ, PDK, PhKγ2, PI 3-Kinase, PIM, Pim-1, Pim-2, Pim-3, PKC, PKCβ1, PKCδ, PKD2, PKR, PKA, PKBβ, PKCβI, PKG1, PKG1α, PKG1β, PLK, PRAK, PTK5, Pyk, Raf, Rct, RIPK2, ROK/ROCK, ROCK-I, Ron, Ros, Rse, Rsk4, Rsk/MAPKAP Kinase, S6 Kinase, Rsk2, SAPK2a, SGK, c-Src, Src(1-530), Src, Syk, TAK1, TA01, TAO2, TBK, Tie2/TEK, TLK2, Trk, TSSK2, TrkA, Txk, ULK3, Ulk2, VRK2, WEE, Yes, ZAP-70 and ZIPK. |
