ANTI-HUMAN PIVKA-II ANTIBODY, HYBRIDOMA AND METHOD FOR IMMUNOLOGICAL MEASUREMENT

摘要

PURPOSE:To obtain a new monoclonal antibody useful for immunological determination of human PIVKA-II. CONSTITUTION:A monoclonal antibody (immunoglobulin class is IgG) specifically reacting with human PIVKA-II but not human prothrombin and human thrombin. The monoclonal antibody is obtained by culturing a hybridoma of mammalian spleen cells immunized against artificial human PIVKA-II prepared by decarboxylating human prothrombin and mammalian myeloma cells.