发明名称 PHARMACEUTICAL COMPOSITIONS FOR PREVENTING OR TREATING TH1 AND TH2 CELL RELATED DISEASES BY MODULATING THE TH1/TH2 RATIO.
摘要 Pharmaceutical composition for preventing or treating a Th1 cell- or Th2-cel l- related disease in a human or an animal by modulating the Th1/Th2 ratio comprising an active substance consisting of (i) IL-4 and SDF-1.alpha., or I L- 2 and SDF-1.alpha., respectively, as well as modulators thereof, (ii) an IL- 4 stimulating adjuvant and SDF-1.alpha., or an IL-2 stimulating adjuvant and S DF- 1.alpha., respectively, (iii) a modulator of the tyrosine kinases Syk or ZAP - 70, or (iv) a modulator of the nuclear factors of activated T cells NFAT1 or NFAT2.
申请公布号 CA2447360(A1) 申请公布日期 2002.11.14
申请号 CA20022447360 申请日期 2002.05.07
申请人 ALK-ABELLO A/S 发明人 POULSEN, LARS KAERGAARD;JINQUAN, TAN
分类号 A61K31/00;A61K31/7088;A61K31/7125;A61K33/06;A61K33/24;A61K33/40;A61K33/42;A61K38/00;A61K38/17;A61K38/19;A61K38/20;A61K39/35;A61K39/39;A61K39/395;A61K45/00;A61K48/00;A61P31/04;A61P35/00;A61P37/00;A61P37/06;A61P43/00;C12N5/0783;C12Q1/48;G01N33/50;(IPC1-7):C07H21/00;A61K31/708;C12Q1/68;C12N5/00;A61P31/00;A61K31/712;A61K38/45;C12Q1/02;C12N5/08;C12N15/11 主分类号 A61K31/00
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