发明名称 |
Biphenyl-3-carboxylic acid modulators of beta-3-adrenoreceptor |
摘要 |
The present invention relates to new biphenyl-3-carboxylic acid modulators of beta-3-adrenoceptor activity, pharmaceutical compositions thereof, and methods of use thereof.; |
申请公布号 |
US9394239(B2) |
申请公布日期 |
2016.07.19 |
申请号 |
US201414297249 |
申请日期 |
2014.06.05 |
申请人 |
Auspex Pharmaceuticals, Inc. |
发明人 |
Zhang Chengzhi |
分类号 |
C07C229/52;A61K31/136;A61K31/196;A61K45/06 |
主分类号 |
C07C229/52 |
代理机构 |
Baker & Hostetler, LLP |
代理人 |
Baker & Hostetler, LLP |
主权项 |
1. A method of treating of a beta-3-adrenoceptor-mediated disorder in a patient in need of treatment, comprising administering to the patient a therapeutically effective amount of a compound having the structural formula: wherein each position represented as D has deuterium enrichment of no less than about 10%. |
地址 |
La Jolla CA US |