发明名称 Biphenyl-3-carboxylic acid modulators of beta-3-adrenoreceptor
摘要 The present invention relates to new biphenyl-3-carboxylic acid modulators of beta-3-adrenoceptor activity, pharmaceutical compositions thereof, and methods of use thereof.;
申请公布号 US9394239(B2) 申请公布日期 2016.07.19
申请号 US201414297249 申请日期 2014.06.05
申请人 Auspex Pharmaceuticals, Inc. 发明人 Zhang Chengzhi
分类号 C07C229/52;A61K31/136;A61K31/196;A61K45/06 主分类号 C07C229/52
代理机构 Baker & Hostetler, LLP 代理人 Baker & Hostetler, LLP
主权项 1. A method of treating of a beta-3-adrenoceptor-mediated disorder in a patient in need of treatment, comprising administering to the patient a therapeutically effective amount of a compound having the structural formula: wherein each position represented as D has deuterium enrichment of no less than about 10%.
地址 La Jolla CA US