发明名称 Prostate kallikrein allergen
摘要 Methods for treatment of a Type I allergy in a mammal comprise administering to an individual in need of such treatment a polypeptide of SEQ ID NO: 1 or the mature protein, amino acids 25-260, of the polypeptide of SEQ ID NO: 1, or a fragment of the polypeptide or the mature protein, which fragment shares epitopes for antibodies with the polypeptide or the mature protein, respectively, or a hypoallergenic form thereof that is modified to abrogate or attenuate its IgE binding response. Diagnostic kits comprise the polypeptide of SEQ ID NO: 1 or the mature protein, amino acids 25-260, of the polypeptide of SEQ ID NO: 1, immobilized on a solid support.
申请公布号 US9518987(B2) 申请公布日期 2016.12.13
申请号 US201514930737 申请日期 2015.11.03
申请人 PHADIA AB 发明人 Mattsson Lars;Lidholm Jonas;Everberg Henrik
分类号 A61K39/00;A61K38/00;A61K39/395;C07K1/00;C07K2/00;C07K4/00;C07K5/00;C07K7/00;C07K14/00;C07K16/00;C07K17/00;G01N33/53;G01N33/573;A61K39/35;C07K16/18;G01N33/68 主分类号 A61K39/00
代理机构 Porter Wright Morris & Arthur LLC 代理人 Porter Wright Morris & Arthur LLC
主权项 1. A method for treatment of a Type I allergy in a mammal, comprising administering to an individual in need of such treatment a polypeptide of SEQ ID NO: 1 or the mature protein, amino acids 25-260, of the polypeptide of SEQ ID NO: 1, or a fragment of the polypeptide or the mature protein, which fragment shares epitopes for antibodies with the polypeptide or the mature protein, respectively.
地址 Uppsala SE