发明名称 RAPIDLY SOLUBLE COATING AGENT COMPOSITION AND ITS PRODUCTION
摘要 PROBLEM TO BE SOLVED: To produce a rapidly soluble coating agent composition, rapidly soluble at normal temperatures in spite of a solid plasticizer contained therein, hardly separating a pigment and capable of forming a film by coating thereof on a tablet such as a medicine. SOLUTION: This rapidly soluble coating agent composition is obtained by adding and mixing a plasticizer which is a solid at normal temperatures and a pigment with a coating base and then heating the resultant mixture at the solidifying point of the plasticizer or above. The coating base is a granular hydroxypropyl methyl cellulose or methyl cellulose having 200-1000μm average grain diameter and the content of the grains having <=75μm grain diameter is <=30wt.%. The plasticizer is at least one selected from polyethylene glycol having 950-25000 weight-average molecular weight and blended in an amount of 5-30wt.% based on the coating base. Titanium oxide or iron oxide or both are used as the pigment and blended in an amount of 1-30wt.% based on the coating base. An aqueous coating agent can rapidly be prepared without requiring a special dissolving apparatus and a constant color tone can always be reproduced.
申请公布号 JPH0959146(A) 申请公布日期 1997.03.04
申请号 JP19950213561 申请日期 1995.08.22
申请人 SHIN ETSU CHEM CO LTD 发明人 KOKUBO HIROYASU
分类号 A61K9/36;A61K47/02;A61K47/34;A61K47/38;(IPC1-7):A61K9/36 主分类号 A61K9/36
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