发明名称 |
PRODUCTION OF VIRUSES, VIRAL ISOLATES AND VACCINES |
摘要 |
The present invention discloses methods for producing and/or propagating virus particles, such as influenza virus particles, that are present in a virus isolate obtained from an infected subject by contacting a host cell with a virus particle and culturing the cell under conditions conducive to propagation of the virus particle. The invention also provides a method for selective propagation of a set of virus particles, such as influenza virus particles present in an influenza isolate, which have an affinity for receptors comprising a specific glycosylation residue. |
申请公布号 |
PT1465987(E) |
申请公布日期 |
2008.04.15 |
申请号 |
PT20020786227T |
申请日期 |
2002.12.09 |
申请人 |
CRUCELL HOLLAND B.V. |
发明人 |
MARIA GRAZIA PAU;GIUSEPPE MARZIO;DIRK JAN ELBERTUS OPSTELTEN;ALPHONSUS GERARDUS, CORNELIS MARIA UYTDEHAAG |
分类号 |
C12N7/00;C12N15/09;A61K39/00;A61K39/145;C07K14/11;C12N5/10;C12N5/22 |
主分类号 |
C12N7/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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