发明名称 Compounds Derived From Lidocaine, Pharmaceutical Compositions, Use And Method Of Treatment, Prevention Or Inhibition Of Disease
摘要 The present invention relates to lidocaine derived compounds, which present less anesthetic activity than lidocaine itself, but with more anti-inflammatory and spasmolytic activity than said lidocaine as well as pharmaceutical compositions with at least one of these compounds or a salt of those as active principle and to the use of such compositions to treat, prevent or inhibit atopic diseases including asthma, rhinitis, allergic urticaria, chronic lung inflammation associated with eosinophilia, following the example of atopic asthma and chronic intestinal inflammation, as colitis for instance. The pharmaceutical composition may be available in spray form, solution, suspension, emulsion destinated to be applied by nebulization, or in any of the pharmaceutical available forms for oral or injectable use.
申请公布号 US2008221206(A1) 申请公布日期 2008.09.11
申请号 US20050570234 申请日期 2005.06.07
申请人 FUNDCAO OSWALDO CRUZ-FIOCRUZ 发明人 MARTINS MARCO AURELIO;DA COSTA JORGE CARLOS SANTOS;BOECHAT NUBIA;SIQUEIRA RODRIGO DE AZEREDO
分类号 A61K31/36;C07C237/20;A61K31/167;A61K31/497;A61K31/5377;A61P11/00;A61P11/06;C07C233/00;C07C237/04;C07D295/155;C07D307/79;C07D317/48;C07D317/66;C07D405/12;C07D413/12 主分类号 A61K31/36
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