| 发明名称 | Immunogenic proteins of <i>Leptospira</i> | ||
| 摘要 | The invention provides novel immunogenic proteins LigA and LigB from Leptospira for use in the development of effective vaccines and antibodies, as well as improved diagnostic methods and kits. | ||
| 申请公布号 | US9366671(B2) | 申请公布日期 | 2016.06.14 |
| 申请号 | US201514876007 | 申请日期 | 2015.10.06 |
| 申请人 | Cornell Research Foundation, Inc. | 发明人 | Chang Yung-Fu;Palaniappan Raghavan U. M. |
| 分类号 | C07K14/20;G01N33/569 | 主分类号 | C07K14/20 |
| 代理机构 | LeClairRyan, a Professional Corporation | 代理人 | LeClairRyan, a Professional Corporation |
| 主权项 | 1. A device comprising a solid surface, wherein at least one antibody is immobilized on the solid surface, wherein such antibody can specifically bind to a LigB protein from Leptospira interrogans, wherein the LigB protein is characterized in that it is a protein (i) comprising SEQ ID NO: 4, SEQ ID NO: 34, or SEQ ID NO: 46, or (ii) consisting of at least 9 contiguous amino acids of SEQ ID NO: 46. | ||
| 地址 | Ithaca NY US | ||