| 发明名称 |
Thyroid hormone action indicator transgenic mouse and recombinant dna construct |
| 摘要 |
A transgenic animal model that is suitable for the cell or tissue specific assessing of thyroid hormone (TH) action in vivo is described. The recombinant DNA construct and methods suitable to generate such an animal are also provided. The assessment of TH action is based on a reporter that is dependent on an endogenously expressed thyroid hormone receptor (TR) and coregulators of said receptor. |
| 申请公布号 |
HU1400563(A2) |
申请公布日期 |
2016.06.28 |
| 申请号 |
HU20140000563 |
申请日期 |
2014.11.28 |
| 申请人 |
MAGYAR TUDOMANYOS AKADEMIA KISERLETI ORVOSTUDOMANYI KUTATOINTEZET |
发明人 |
FEKETE CSABA;GEREBEN BALAZS;MOHACSIK PETRA;ERDELYI FERENC;SZABO GABOR |
| 分类号 |
C12N15/00;A61K49/00;C12N15/09;C12N15/63;C12N15/65 |
主分类号 |
C12N15/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
