METHODS AND COMPOSITIONS FOR ASSESSING PATIENTS WITH PREECLAMPSIA-RELATED CONDITIONS USING MICRORNA

摘要

The invention is directed to methods and compositions for collecting a non-placental biological samples of cells and quantifying and comparing levels of expression of microRNAs to characterize a preeclampsia-related condition. The samples may be collected before or after an intervention or may be collected over a period of time. One of the samples may be a control sample. Patients may then be treated according to their response.

主权项

1. A method for characterizing a preeclampsia-related condition in a subject comprising:
collecting a first non-placental biological sample; extracting microRNA-comprising RNA from the first non-placental biological sample; quantifying at least one microRNA within the extracted RNA; and comparing the quantification of the at least one microRNA to a quantification of the at least one microRNA from a second, non-placental biological sample.