Ophthalmic lens molds with low levels of UV light transmittance, ophthalmic lenses molded therein, and related methods

摘要

Ophthalmic lens molds made from one or more thermoplastic polymer having a low level of UV light transmittance (UV % T) ophthalmic lenses including silicone hydrogel contact lenses molded using these thermoplastic polymer having low UV % T, and methods of manufacturing ophthalmic lenses by cast molding a polymerizable composition in mold members formed of these thermoplastic polymers having low UV % T and curing the polymerizable composition using UV light are described.

主权项

1. A method of manufacturing a silicone hydrogel contact lens body, comprising:
providing a first mold member and a second mold member, the first mold member comprising a concave molding surface configured to mold an anterior surface of a contact lens and the second mold member comprising a convex molding surface configured to mold a posterior surface of a contact lens, the molding surface of at least one of the first mold member and the second mold member comprising at least one thermoplastic polymer having a level of UV transmittance of from 0.01% to 3.00%, the first mold member and the second mold member being configured to form a lens-shaped cavity therebetween when combined as a mold assembly; placing a polymerizable composition comprising a) at least one silicon-containing monomer, silicon-containing macromer, silicon-containing prepolymer, or any combination thereof, and b) at least one hydrophilic monomer in the first mold member; assembling the mold assembly by placing the second mold member in contact with the first mold member so as to form a lens-shaped cavity therebetween with the polymerizable composition contained in the lens-shaped cavity of the mold assembly; and directing UV light through the mold assembly into the lens-shaped cavity to cure the polymerizable composition in the mold assembly, forming a cast-molded polymerized reaction product in the lens-shaped cavity of the mold assembly, the polymerized reaction product comprising a silicone hydrogel contact lens body, wherein the level of UV transmittance of the at least one thermoplastic polymer is determined at 370 nm using a sample of the thermoplastic polymer having a thickness of from 0.6 mm to 0.7 mm, and the at least one thermoplastic polymer has a high level of UV light diffusivity, and is effective to reduce variation in UV light intensity between an exterior surface of the mold assembly and the lens-shaped cavity by at least 5% during the step of directing UV light.