METHOD OF INHIBITING MUTANT C-KIT

摘要

The present invention includes a method of reducing or inhibiting the kinase activity of C-KIT mutant tyrosine kinase activity in a cell or a subject, and the use of such compound for treating mutant C-KIT driven cell proliferative disorder(s) in a subject related to using a compound of the present invention:;;or pharmaceutically acceptable salt thereof.

主权项

1. A method of inhibiting or reducing mutant C-KIT tyrosine kinase activity or expression in a subject suffering from a proliferative disease which comprises administering to the subject having or suspected to have the proliferative disease, a therapeutically effective amount of the compound of Formula I:or a pharmaceutically acceptable salt or solvate thereof.