Process for introducing a thiocarboxylic ester group at the ortho-position of phenols or phenylamines.

摘要

A process for introducing thiocarboxylic ester at ortho-position of phenols or phenylamines which comprises reacting a phenyl compound having hydroxy group or optionally substituted amino or cyclic amino group, of which at least one ortho-position is vacant, with C1 - C5 alkyl thiocyanate, C7 - C13 aralkyl thiocyanate or C6 - C12 aryl thiocyanate in the presence of a boron trihalide and hydrolyzing the resultant product under acidic conditions is provided, and said process is useful in the synthesis of medicinals, pesticides and dyes.