| 摘要 |
Compounds represented by general formula (1) and having a selective antagonism to NK2 receptors and pharmacologically acceptable salts or derivatives thereof, wherein R1 represents optionally substituted cycloalkyl or an optionally substituted saturated heterocycle; R2 represents aryl, etc.; A represents methylene, etc.; B represents a single bond, alkylene, etc.; D represents oxygen or sulfur; G represents alkylene, etc.; L represents -N(R3)-or -C(R4)(R5)- ¢wherein R3 represents aryl, etc.; R4 represents aryl, etc.; and R5 represents optionally aminated alkyl or -CO-R6 (wherein R6 represents alkyl, etc.); or R4 and R5 may form together a cycloalkane ring, etc.!; R7 represents alkyl; Z represents two hydrogen atoms or an oxygen atom; and n is 0, 1 or 2.
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