摘要 |
The invention provides a biosynthetic gene cluster for mitomycin, for example, a mitomycin biosynthetic cluster from organisms such as Streptomyces, for instance, S. lavendulae, as well as methods of using gene(s) within the cluster to alter antibiotic biosynthesis and to prepare a polyketide synthase. |
申请人 |
REGENTS OF THE UNIVERSITY OF MINNESOTA;SHERMAN, DAVID H.;MAO, YINGQING;VAROGLU, MUSTAFA;HE, MIN;SHELDON, PAUL C. |
发明人 |
SHERMAN, DAVID, H.;MAO, YINGQING;VAROGLU, MUSTAFA;HE, MIN;SHELDON, PAUL, C. |