Compositions for transdermal delivery of active agents

摘要

Disclosed herein are compositions that are useful in effecting the transdermal delivery of therapeutic agents. More particularly, the disclosed transdermal compositions may include a fatty alcohol (for example, octanol), a terpene (for example, limonene), and an active agent comprising an amine moiety.

主权项

1. A pharmaceutically acceptable transdermal composition comprising octanol, a terpene, an organic acid, and an active agent or pharmaceutically acceptable salts thereof, wherein the transdermal composition, when transdermally administered to a patient, delivers more than twice the amount of the active agent to said patient over 20 hours as compared to a formulation that does not include octanol; a formulation that does not include hydrocarbon terpene; or a formulation that does not include an organic acid.