H:/ft/interwoven/NRPortbl/DCC/FMT/I 1455633_ .docx-9/22/2016 The present invention relates to polypeptides directed against or specifically binding to chemokine receptor CXCR2 and in particular to polypeptides capable of modulating signal transduction from CXCR2. The invention also relates to nucleic acids, vectors and host cells capable of expressing the polypeptides of the invention, pharmaceutical compositions comprising the polypeptides and uses of said polypeptides and compositions for treatment of diseases involving aberrant functioning of CXCR2.
申请公布号
AU2016234907(A1)
申请公布日期
2016.10.20
申请号
AU20160234907
申请日期
2016.09.28
申请人
Novartis AG
发明人
Bradley, Michelle;Brown, Zarin;Charlton, Steven John;Cromie, Karen;Dombrecht, Bruno;Steffensen, Soren;Van Heeke, Gino