发明名称 |
Substituted spirocydic inhibitors of autotaxin |
摘要 |
The present invention relates to compounds according to Formula 1 and pharmaceutically acceptable salts, synthesis, intermediates, formulations, and methods of disease treatment therewith, including cancer, lymphocyte homing, chronic inflammation, neuropathic pain, fibrotic diseases, thrombosis, and cholestatic pruritus, mediated at least in part by ATX. |
申请公布号 |
AU2015240519(A1) |
申请公布日期 |
2016.10.20 |
申请号 |
AU20150240519 |
申请日期 |
2015.04.03 |
申请人 |
X-Rx, Inc. |
发明人 |
Babiss, Lee;Clark, Matthew;Keefe, Anthony D.;Mulvihill, Mark J.;Ni, Haihong;Renzetti, Louis;Ruebsam, Frank;Wang, Ce;Xie, Zhifeng;Zhang, Ying |
分类号 |
C07D209/96;A61K31/503;C07D221/20 |
主分类号 |
C07D209/96 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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