发明名称 Microneedle roller (MNR) infusion system
摘要 A micro-needle roller (MNR) infusion system for transdermal delivery of active agents, skin-care products, and other topical formulations is described herein. The infusion system of the instant invention comprises a needle roller assembly with needles enclosed in a housing with a vacuum line and a disposable cartridge having the active agent, the skin-care product or the topical formulation. The vacuum delivers the fluid and ensures that the skin is being pulled against the needle wheel surface to ensure that penetration of the needles is complete into the skin, simultaneously the fluid is flowing to the wheel and to skin as it rolls along with the outer housing of the tip cap assembly being occluded to the skin surface.
申请公布号 US9504813(B2) 申请公布日期 2016.11.29
申请号 US201514957213 申请日期 2015.12.02
申请人 GENESIS BIOSYSTEMS, INC. 发明人 Buss Brian
分类号 A61M37/00;A61M5/31;A61M5/32;A61M5/42;A61M5/46;A61M5/158 主分类号 A61M37/00
代理机构 Chalker Flores, LLP 代理人 Flores Edwon S.;Chalker Daniel J.;Chalker Flores, LLP
主权项 1. A device for a transdermal delivery of one or more active agents, skin-care products, topical formulations or combinations thereof to a subject comprising: a housing comprising a cavity, wherein the cavity is adapted to receive one or more gas lines, vacuum lines or both, one or more reservoirs, cartridges or compartments, and one or more active agents contained in the cavity or in the removable reservoirs, cartridges or compartments; and a tip cap assembly removably attached to the housing assembly, wherein the tip cap assembly encloses a skin penetrating device in fluid connection with the cavity in the housing, wherein the skin penetrating device comprises a micro-needle roller comprising one or more micro-needles attached to and supported by a roller surface, wherein a movement of the roller over the skin of the subject causes a rotation of the roller and brings the micro-needles into contact with the skin of the subject through an opening in the tip cap assembly resulting in a penetration of the skin and the transdermal delivery of the one or more active agents, skin-care products, topical formulations or combinations thereof present on the roller, wherein the one or more active agents, the skin-care products, the topical formulations or combinations thereof is drawn from the cavity, one or more removable reservoirs, cartridges or compartments by a vacuum pulled through the vacuum line.
地址 Lewisville TX US