主权项 |
1. A device for a transdermal delivery of one or more active agents, skin-care products, topical formulations or combinations thereof to a subject comprising:
a housing comprising a cavity, wherein the cavity is adapted to receive one or more gas lines, vacuum lines or both, one or more reservoirs, cartridges or compartments, and one or more active agents contained in the cavity or in the removable reservoirs, cartridges or compartments; and a tip cap assembly removably attached to the housing assembly, wherein the tip cap assembly encloses a skin penetrating device in fluid connection with the cavity in the housing, wherein the skin penetrating device comprises a micro-needle roller comprising one or more micro-needles attached to and supported by a roller surface, wherein a movement of the roller over the skin of the subject causes a rotation of the roller and brings the micro-needles into contact with the skin of the subject through an opening in the tip cap assembly resulting in a penetration of the skin and the transdermal delivery of the one or more active agents, skin-care products, topical formulations or combinations thereof present on the roller, wherein the one or more active agents, the skin-care products, the topical formulations or combinations thereof is drawn from the cavity, one or more removable reservoirs, cartridges or compartments by a vacuum pulled through the vacuum line. |