发明名称 Cholesterol lowering compounds
摘要 Disclosed herein are compounds of structural formula (I) <IMAGE> (I) which are useful as cholesterol lowering agents. These compounds are also useful as inhibitors of squalene synthase, inhibitors of fungal growth, inhibitors of farnesyl-protein transferase and farnesylation of the oncogene protein Ras. These compounds are also useful in the treatment of cancer.
申请公布号 US5258401(A) 申请公布日期 1993.11.02
申请号 US19920938981 申请日期 1992.09.10
申请人 MERCK & CO., INC. 发明人 BERGER, GREGORY D.;MARQUIS, JR., ROBERT W.;ROBICHAUD, ALBERT J.;SCOLNICK, EDWARD M.
分类号 C07D493/08;(IPC1-7):A61K31/335;A61K31/365;A61K31/38;A61K31/34;C07D319/04;C07D405/06;C07D405/08;C07D407/06 主分类号 C07D493/08
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