发明名称 |
Cholesterol lowering compounds |
摘要 |
Disclosed herein are compounds of structural formula (I) <IMAGE> (I) which are useful as cholesterol lowering agents. These compounds are also useful as inhibitors of squalene synthase, inhibitors of fungal growth, inhibitors of farnesyl-protein transferase and farnesylation of the oncogene protein Ras. These compounds are also useful in the treatment of cancer.
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申请公布号 |
US5258401(A) |
申请公布日期 |
1993.11.02 |
申请号 |
US19920938981 |
申请日期 |
1992.09.10 |
申请人 |
MERCK & CO., INC. |
发明人 |
BERGER, GREGORY D.;MARQUIS, JR., ROBERT W.;ROBICHAUD, ALBERT J.;SCOLNICK, EDWARD M. |
分类号 |
C07D493/08;(IPC1-7):A61K31/335;A61K31/365;A61K31/38;A61K31/34;C07D319/04;C07D405/06;C07D405/08;C07D407/06 |
主分类号 |
C07D493/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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