摘要 |
<p>The invention relates to a device for automated bioreactor sampling connected to a reactor (1) comprising a sampler (4), at least one tube (21,22) fluidly connecting said reactor (1) with said sampler (4) and a pump (9) for pumping fluids from said reactor (1) to said sampler (4) and vice versa. Particularly simple and essentially dead volume-free sampling can be achieved by providing means (3,14) for flushing at least parts of the tube (21,22) with gas/sterile air between individual sampling steps. The invention furthermore relates to a method of operation of such a device. <IMAGE></p> |