| 发明名称 |
High throughput screening assays using fatty acid synthetic enzymes |
| 摘要 |
High throughput screening assays for the identification of potential therapeutic agents able to modulate the activity of enzymes of fatty acid biosynthesis, especially desaturases and/or elongases, are disclosed along with therapeutic uses of the agents identified by such assays for the prevention and/or treatment of diseases related to fatty acid metabolism. Substrates useful in such assays are also described.
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| 申请公布号 |
US7294480(B2) |
申请公布日期 |
2007.11.13 |
| 申请号 |
US20040827668 |
申请日期 |
2004.04.19 |
| 申请人 |
XENON PHARMACEUTICALS INC. |
发明人 |
WINTHER MICHAEL D.;GRAY-KELLER MARK P. |
| 分类号 |
C12Q1/26;A61K45/00;A61P1/04;A61P1/14;A61P3/06;A61P3/10;A61P9/00;A61P11/00;A61P15/00;A61P17/00;A61P17/04;A61P19/02;A61P19/04;A61P25/00;A61P25/32;A61P29/00;A61P31/12;A61P35/00;A61P37/00;A61P43/00;C12Q1/48;G01N33/60 |
主分类号 |
C12Q1/26 |
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