发明名称 |
FABRY DISEASE GENE THERAPY |
摘要 |
There is described a nucleic acid molecule comprising a nucleotide sequence encoding for a functional α-galactosidase A protein wherein the nucleotide sequence has at least 85% identity to the sequence of SEQ ID NO. 1. Also described is a vector, host cell or transgenic animal comprising the nucleic acid molecule; and a pharmaceutical composition comprising the nucleic acid molecule or the vector. Further, the use of the nucleic acid molecule in a method of treating Fabry disease is described. |
申请公布号 |
WO2016181122(A1) |
申请公布日期 |
2016.11.17 |
申请号 |
WO2016GB51328 |
申请日期 |
2016.05.10 |
申请人 |
UCL BUSINESS PLC |
发明人 |
NATHWANI, Amit;RAJ, Deepak |
分类号 |
A61K48/00;C12N9/40;C12N15/67;C12N15/864 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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