发明名称 |
TREATING VASCULATURE RELATED DISEASES OR DISORDERS USING NANOPARTICLES |
摘要 |
The present invention relates to prevention and/or treatment of diseases or disorders associated with a damaged or leaky vasculature in a subject. The present invention provides for methods, combinations and pharmaceutical compositions for preventing and/or treating a disease or disorder associated with a damaged or leaky vasculature in a subject, using, inter alia, an effective amount of a nanoparticle comprising an inner core comprising a non-cellular material, an outer surface comprising a cellular membrane derived from a platelet; and optionally an agent for preventing, treating, diagnosing, or prognosing the disease or disorder and/or monitoring prevention or treatment of the disease or disorder. Exemplary diseases or disorders include hemorrhage (bleeding), cardiovascular diseases or disorders, diseases or disorders associated with narrowing of a blood vessel, tumors or cancers. |
申请公布号 |
WO2016205010(A1) |
申请公布日期 |
2016.12.22 |
申请号 |
WO2016US36139 |
申请日期 |
2016.06.07 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
ZHANG, Liangfang;HU, Che-Ming Jack;FANG, Ronnie H.;LUK, Brian T.;WANG, Kuei-Chun;CHIEN, Shu |
分类号 |
A61K9/14;A61K9/50;A61K9/51;A61K9/64;B82Y5/00;B82Y30/00 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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