| 发明名称 |
REDIRECTION OF CELLULAR IMMUNITY BY RECEPTOR CHIMERAS |
| 摘要 |
Disclosed is a method of directing a cellular response in a mammal by expressing in a cell of the mammal a chimeric receptor which causes the cells to specifically recognize and destroy an infective agent, a cell infected with an infective agent, a tumor or cancerous cell, or an autoimmune-generated cell. Also disclosed are cells which express the chimeric receptors and DNA encoding the chimeric receptors. |
| 申请公布号 |
WO9215322(A1) |
申请公布日期 |
1992.09.17 |
| 申请号 |
WO1992US01785 |
申请日期 |
1992.03.06 |
| 申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
SEED, BRIAN;ROMEO, CHARLES;KOLANUS, WALDEMAR |
| 分类号 |
A61K35/12;A61K35/14;A61K38/00;A61K39/395;A61K39/42;A61K48/00;A61P35/00;A61P37/00;C07K14/00;C07K14/705;C07K14/725;C07K14/73;C07K14/735;C07K16/00;C07K19/00;C12N5/00;C12N5/10;C12N9/12;C12N15/00;C12N15/09;C12N15/62;C12N15/63;C12P21/08 |
主分类号 |
A61K35/12 |
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