发明名称 Piperidines and piperazines
摘要 Piperidine and piperazine derivatives of formula I <IMAGE> I wherein R1 and R2 are H or A, R3, R4 and R5 are each independently H, Hal, OH, OA, OAc, NO2, NH2, NHAc, NHSO2A or CN, or R3 and R4 together are -O-(CH2)m-O-, n is 0, 1 or 2 X is O or CH2, if n=0 or 2, or CH2, NH, NA or NAc, if n=1, Y is CH or N, m is 1 or 2, Hal is F, Cl, Br or I, A is C1-6-alkyl, Ac is C1-8-alkanoyl C1-10-aralkanoyl or C7-11-aroyl, and their physiologically acceptable salts show antiarrhythmic effects.
申请公布号 US5495022(A) 申请公布日期 1996.02.27
申请号 US19940264872 申请日期 1994.06.24
申请人 MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG 发明人 BAUMGARTH, MANFRED;LUES, INGE;MINCK, KLAUS-OTTO;BEIER, NORBERT
分类号 A61K31/445;A61K31/4427;A61K31/443;A61K31/451;A61K31/47;A61K31/495;A61P9/06;C07D211/14;C07D211/18;C07D211/22;C07D211/26;C07D211/28;C07D211/34;C07D215/12;C07D295/04;C07D295/08;C07D295/096;C07D307/81;C07D313/08;C07D319/18;C07D401/06;C07D405/06;C07D405/14;(IPC1-7):C07D211/22;A61K31/455 主分类号 A61K31/445
代理机构 代理人
主权项
地址
您可能感兴趣的专利