发明名称 |
PROCESS FOR PRODUCING PAROXETINE HYDROCHLORIDE HYDRATE |
摘要 |
<p>A process for preparing a paroxetine hydrochloride hydrate, comprising reacting (3S, 4R)-1-tert-butoxycarbonyl-4-(4-fluorophenyl)-3-Ä(3,4-methylenedioxy)phenoxymethylÜpiperidine with hydrogen chloride in the presence of water, and allowing crystals to separate out from the resulting reaction mixture in the presence of water.</p> |
申请公布号 |
EP1555263(A1) |
申请公布日期 |
2005.07.20 |
申请号 |
EP20030751271 |
申请日期 |
2003.09.17 |
申请人 |
SUMITOMO CHEMICAL COMPANY, LIMITED |
发明人 |
YAMAZAKI, SHIGEYA;YOSHIKAWA, TAICHI |
分类号 |
A61P25/24;A61P25/00;A61P25/04;A61P25/22;A61P25/28;A61P43/00;C07D405/12;(IPC1-7):C07D405/12;A61K31/452 |
主分类号 |
A61P25/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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