| 发明名称 |
AN IMPROVED PROCESS FOR THE PREPARATION OF BIPHOSPHONIC DERIVATIVES |
| 摘要 |
<p>The present invention provides a novel process for preparation of bisphosphonic acid derivatives or pharmaceutical acceptable salt thereof, by reacting carboxylic acid having structural formula (II) with phosphorous acid and a halophosphorous compound, wherein halophosphorous compound is selected from the group comprising of PCl<SUB>3</SUB>, PCl<SUB>5</SUB>, POCl<SUB>3</SUB>, PBr<SUB>3</SUB>, POBr<SUB>3</SUB>, and PBr<SUB>5</SUB> in presence of diphenyl ether.</p> |
| 申请公布号 |
WO2007096896(A1) |
申请公布日期 |
2007.08.30 |
| 申请号 |
WO2006IN00206 |
申请日期 |
2006.06.16 |
| 申请人 |
ALEMBIC LIMITED;DESHPANDE, PANDURANG, BALWANT;LUTHRA, PARVEN, KUMAR |
发明人 |
DESHPANDE, PANDURANG, BALWANT;LUTHRA, PARVEN, KUMAR |
| 分类号 |
C07F9/38;C07F9/58;C07F9/6506;C07F9/6561 |
主分类号 |
C07F9/38 |
| 代理机构 |
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