CONSTRUCCION PEPTIDICA DENDRIMERICA PARA LA PREVENCION DE LA FIEBRE AFTOSA EN ANIMALES.

摘要

This construct is one of formula (I) wherein: T is a peptide comprising the sequence SEQ ID NO: 1 or a fragment thereof; B is a peptide comprising the sequence SEQ ID NO: 2 or a fragment thereof; X is an acyl group bound to the N-terminal end of B; n is 3 or 4; and L corresponds to a lysine core of formula (II) where W is a linker; Z 1 -Z 4 are equal or different to each other and are selected from the group consisting of cysteine and-OH, provided that at least three of the groups Z 1 to Z 4 are cysteine; the peptide B being linked to the lysine core by its C-terminal end and the peptide T being linked to said lysine core by its N-terminal end.
€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ(X-B)n-L-T€ƒ€ƒ€ƒ€ƒ€ƒ(I)