摘要 |
PCT No. PCT/US92/00113 Sec. 371 Date Aug. 27, 1993 Sec. 102(e) Date Sep. 24, 1993 PCT Filed Jan. 17, 1992.The present invention relates to novel 1-azabicyclo[3.2.2]nonan-3-amine derivatives of the formula <IMAGE> I wherein R1, R2, R3, R4, R5 are each independently selected from hydrogen, fluorine, chlorine, bromine, trifluoromethyl, alkyl having from one to three carbon atoms, alkoxy having from one to three carbon atoms, carboxy, alkoxycarbonyl having from one to three carbon atoms in the alkoxy moiety, and benzoyloxycarbonyl. These compounds are useful in the treatment of inflammatory and central nervous system disorders, as well as other disorders.
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