发明名称 |
PROCESS FOR THE PREPARATION OF ABIRATERONE AND ABIRATERONE ACETATE |
摘要 |
;The present invention relates to a novel process for the synthesis of abiraterone, and in particular of abiraterone acetate, compound of formula (I) reported below: N O (I) which has pharmacological activity useful for slowing down the progression of prostate cancer at an advanced stage. The process is characterised by an intermediate step wherein DHEA-acetate is triflated using Ar-N(OTf)2 as the triflation reagent. |
申请公布号 |
US2016168192(A1) |
申请公布日期 |
2016.06.16 |
申请号 |
US201314908816 |
申请日期 |
2013.07.29 |
申请人 |
INDUSTRIALE CHIMICA S.R.L. |
发明人 |
LENNA Roberto;DI BRISCO Riccardo |
分类号 |
C07J43/00;C07J31/00 |
主分类号 |
C07J43/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Milano IT |