发明名称 COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF MEK.
摘要 The present invention relates to compounds of formula I in which n, R1, R2, R3a, R4 and R5 are defined in the Summary of the Invention; capable of inhibiting the activity of MEK. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of hyperproliferative diseases like cancer.
申请公布号 MX2016001980(A) 申请公布日期 2016.06.21
申请号 MX20160001980 申请日期 2014.08.14
申请人 NOVARTIS AG 发明人 MARK GARY BOCK;RAMULU PODDUTOORI;HENRIK MOEBITZ;SUNIL KUMAR PANIGRAHI;SUSANTA SAMAJDAR
分类号 C07D471/04;A61K31/437;A61P35/00 主分类号 C07D471/04
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