发明名称 |
ORGANIC COMPOUNDS |
摘要 |
A process for reducing the tendency of a drug substance to aggregate and/or agglomerate during storage. The process involves micronising the drug substance to give a mean particle size of less than about 10 µm, and exposing the micronised drug substance to a dry environment at an elevated temperature between 40° C and 120° C for at least six hours. |
申请公布号 |
CA2708083(C) |
申请公布日期 |
2016.06.28 |
申请号 |
CA20082708083 |
申请日期 |
2008.12.11 |
申请人 |
NOVARTIS AG |
发明人 |
MUHRER, GERHARD;RASENACK, NORBERT;JUHNKE, MICHAEL |
分类号 |
A61K9/00;A61K9/14;A61K31/4015 |
主分类号 |
A61K9/00 |
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