8-CHLORO-6,11-DIHYDRO-11-(4-PIPERIDYLIDENE)-5H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDINE ORAL COMPOSITIONS

摘要

Stable pharmaceutical compositions containing 8-chloro- 6,11-dihydro- 11-(4- piperidylidene)- 5H-benzo[5,6] cycloheptic [1,2-b] pyridine ("DCL") and a DC L protective amount of a pharmaceutically acceptable basic salt such as calciu m dibasic phosphate and an amount of at least one disintegrant, preferably two disintegrates such as microcrystalline cellulose and starch sufficient to provide dissolution of at least about 80 % by weight of the pharmaceutical composition in about 45 minutes and suitable for oral administration to trea t allergic reactions in mammals such as man are disclosed.