MELANOMA CELL LINES EXPRESSING SHARED IMMUNODOMINANT MELANOMA ANTIGENS AND METHODS OF USING THE SAME

摘要

PROBLEM TO BE SOLVED: To provide melanoma cell lines expressing shared immunodominant melanoma antigens, having effects which are not realized by conventional technologies, and to provide methods for using the cell lines.

SOLUTION: A method of treating or preventing melanoma comprises (a) obtaining a melanoma cell line which expresses one or more shared immunodominant melanoma antigens, (b) modifying the melanoma cell line to render it capable of increasing a producing level of a cytokine relative to the unmodified cell line, and (c) administering the melanoma cell line to a mammalian host that has melanoma or is at risk for developing melanoma.

COPYRIGHT: (C)2008,JPO&INPIT