发明名称 Styrenic ophthalmic and otorhinolaryngological materials and devices formed therewith
摘要 Disclosed are improved ophthalmic and otorhinolaryngological device materials and devices formed therewith. The device materials are soft, high refractive index styrenic device materials that are used to form the ophthalmic or otorhinolaryngological devices, particularly ophthalmic implants (e.g., intraocular lenses).
申请公布号 US9372282(B1) 申请公布日期 2016.06.21
申请号 US201213596775 申请日期 2012.08.28
申请人 Novartis AG 发明人 Jiang Xuwei;Laredo Walter R.
分类号 G02B1/04;G02C7/04;A61F2/14;A61F2/16;A61F2/18 主分类号 G02B1/04
代理机构 代理人 Ryan Patrick M.
主权项 1. A polymeric ophthalmic or otorhinolaryngological device material comprising: at least 85 w/w % of a polystyrene of structure (I): wherein: ntot represents values of n, which are separate integer values n=1 through n=ntot; mtot represents values of m, which are separate integer values m=1 through m=mtot; ptot represents values of p, which are separate integer values p=1 through p=ptot; R1 independently=H, CH3, or CH2CH3; R2 independently=H or R3; and R3 is independently=linear alkyl, branched alkyl, alkyl ether, alkoxy, ester or any combination thereof for each separate combination of values of n and p and m and p; A=independently, nothing or a connector moiety; B=independently, nothing or a connector moiety; ntot=is independently 1 or greater for each value of p; mtot=is independently 1 or greater for each value of p; and ptot=5 or greater; and wherein, numerically, R2=R3 at least 50% of the time and wherein the device material is shaped into a device selected from the group consisting of intraocular lenses; contact lenses; keratoprostheses; corneal inlays or rings; otological ventilation tubes; and nasal implants; and wherein the polystyrene of structure (I) is formed by the polymerization of styrene monomers of the following structure (II):and wherein the polystyrene of structure (I) is formed from at least 90% but no greater than 97% of the monomers of structure (II) polymerized to form the device material; wherein the device material has a refractive index in the dry state of at least 1.47, an elongation of at least 150% and a Young's modulus of less than 6.0 MPa.
地址 Basel CH