BIOMARKER TEST FOR PREDICTION OR EARLY DETECTION OF PREECLAMPSIA AND/OR HELLP SYNDROME

摘要

Disclosed are specific biomarkers that allow for early testing of preeclampsia/HELLP syndrome. Thus, a method is provided predicting preeclampsia in a pregnant woman. Also disclosed is a kit comprising means for assaying a sample from a pregnant woman for the concentrations of the specific biomarkers.

主权项

1. A method for assessing the presence or risk of preeclampsia/HELLP syndrome, in a female to determine the need for a treatment regimen comprising:
determining levels of one or more of complement factor B; gelsolin isoform a precursor; hornerin, fetuin B; hemopexin precursor; apolipoprotein H precursor; fms-related tyrosine kinase 1; hydroxysteroid (17-β) dehydrogenase 1; leptin; lectin galactoside-binding soluble 14; pappalysin 2; or placenta-specific 1 in a biological sample obtained from the female; generating a dataset based on the determined levels; assessing the presence or risk of developing preeclampsia in the female based on the dataset; and determining a treatment regimen based on the assessed presence or risk.